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Karyn L. Hamilton, R.D., Ph.D.

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Research Interests

• The broad interest areas for my research are the mechanism(s) of exercise- and estrogen-induced protection of the heart and vascular endothelium against hypoxia-reoxygenation injury.

Education

• 2000-2002, Post-Doctoral Research Fellow, Baylor College of Medicine, Houston, TX
• 2000, Ph.D. Exercise Physiology, University of Florida, Gainesville, FL
• 1996 M.S. Exercise Physiology, Montana State University, Bozeman, MT
• 1989 B.S. Nutrition, Montana State University, Bozeman, MT

Professional Experience

• 2004 (current) Assistant Professor, Health and Exercise Science, College of Applied Sciences, Colorado State University, Fort Collins, CO
• 2002-2004 Assistant Scientist, Center for Exercise Science, College of Health and Human Performance, University of Florida, Gainesville, FL
• 2000-2002 Post-Doctoral Research Fellow, Cardiology Section, Department of Medicine, Baylor College of Medicine, Houston, TX
• 1998-2000 Adjunct Faculty, Sciences for Health Professions, Santa Fe Community College, Gainesville, FL
• 1996-2000 Graduate Teaching/Research Assistant, Center for Exercise Science, Department of Exercise and Sport Sciences, University of Florida, Gainesville, FL
• 1994-1996 Graduate Teaching Assistant/Technician, Human Performance & Ergonomics Laboratory, Department of Health and Human Development, Montana State University, Bozeman, MT
• 1990-1994 Clinical Nutrition Support Dietitian, Harborview Medical Center/ University of Washington Medical Center, University of Washington, Seattle, WA
• 1989-1990 Clinical Nutrition Support Dietitian, University of California San Francisco Medical Center, San Francisco, CA

Honors and Awards

• American Physiological Society, Genome and Hormones Meeting, Outstanding Young Investigator Award, 2001
• Outstanding Graduate Research Award, University of Florida, Gainesville, FL, 2000
• Grinter Fellowship Recipient, University of Florida, Gainesville, FL, 1997-2000
• Outstanding Graduate Student Award, College of Health and Human Performance, University of Florida, 1999
• Outstanding Graduate Student Award, College of Education, Health, and Human Development, Montana State University, 1996
• Outstanding Clinical Dietetic Intern Award, University of California, San Francisco, 1989-1990
• Registered Dietitian, Commission on Dietetic Registration, 1989-present

Current Classes Taught

• EX 145 Health and Wellness
• EX 476 Exercise and Chronic Disease

Selected Recent Publications

• Knowlton, A.A., F.N. Mbai and K.L. Hamilton. Estrogen, Heat Shock Proteins and the Cardiovascular System. In Progress in Coronary Artery Disease Proceedings of the 6th International Congress on Coronary Artery Disease. B.S.Lewis, Z.Ongen, M.Y.Flugelman, and D.A.Halon, Editors. Medimond. Bologna, Italy, 6(1):17, 2005.
• Mbai, F.N., K.L. Hamilton and A.A. Knowlton. Gender differences in cardiovascular disease: The effects of estrogen. Drug Discovery Today: Disease Mechanisms. 2:65-70, 2005.
• Hamilton, K.L., J. Quindry, J.P. French, J.L. Staib, J. Hughes, J.L. Mehta and S.K. Powers. MnSOD antisense treatment and exercise-induced protection against arrhythmias. Free Radical Biology and Medicine. 37(9): 1360-1368, 2004.
• Hamilton K.L., F.N. Mbai, S. Gupta, A.A. Knowlton. Estrogen, heat shock proteins, and NFkB in human vascular endothelium. Arteriosclerosis, Thrombosis, and Vascular Biology. 24:1628-1633, 2004.
• Lennon, S.L., J. Quindry, K.L. Hamilton, J.P. French, J. Hughes, J.L. Mehta, and S.K. Powers. Elevated MnSOD is not required for exercise-induced cardioprotection against myocardial stunning. American Journal of Physiology Heart and Circulatory Physiology. 287(2):H975-980, 2004.
• Powers, S.K., J.C. Quindry, and K.L. Hamilton. Aging, exercise, and cardioprotection. Annals of the New York Academy of Sciences. 1019:462-470, 2004.
• Hamilton, K.L., S. Gupta, and A.A. Knowlton. Estrogen and regulation of heat shock protein expression in female cardiomyocytes: Cross-talk with NFkB signaling. Journal of Molecular and Cellular Cardiology. 36(4):579-586, 2004.
• Lennon, S., J. Quindry, K.L. Hamilton, J.P. French, J. Staib, J.L. Mehta, and S.K. Powers. Loss of exercise-induced cardioprotection following cessation of exercise. Journal of Applied Physiology. 96(4):1299-1305, 2004.
• Powers, S.K., K. DeRuisseau, J. Quindry, and K. Hamilton. Dietary antioxidants and exercise. Journal of Sports Sciences 22: 81-94, 2004.
• Vanderford, M.L., M.C. Meyers, W.A. Skelly, C.C. Stewart, and K.L. Hamilton. Physiological and sport-specific skill response of Olympic youth soccer athletes. Journal of Strength and Conditioning Research. 18(2):000-000, 2004.
• Demirel, H.A., K.L. Hamilton, R.A. Shanely, N. Tumer, M. Koroly, and S.K. Powers. Age and attenuation of exercise-induced myocardial HSP72 accumulation. American Journal of Physiology Heart and Circulatory Physiology. 285:H1609-H1615, 2003.
• Hamilton, K.L., S.K. Powers, J.L. Staib, S. Lennon, T. Phillips, and A. Hess. Protective strategies against myocardial ischemia-reperfusion injury: exercise and nutritional antioxidants. Free Radical Biology and Medicine 34: 800-809, 2003.
• Vincent H.K., R.A. Shanely, D.J. Stewart, H.A. Demirel, K.L. Hamilton, A.D. Ray, C. Michlin, G.A. Farkas, S.K. Powers. Adaptation of upper airway muscles to chronic endurance exercise. American Journal of Respiratory and Critical Care Medicine. 166:287-293, 2002.
• Hamilton, K.L., S.K. Powers, T. Sugiura, S. Kim, S. Lennon, N. Tumer, and J.L. Mehta. Short-term exercise training can improve myocardial tolerance to I/R without elevation in heat shock proteins. American Journal of Physiology Heart and Circulatory Physiology. 281:H1346-H1352, 2001.
• Coombes, J.S., S.K. Powers, B. Rowell, K.L. Hamilton, S.L. Dodd, R.A. Shanely, C.K. Sen, and L. Packer. Effects of vitamin E and alpha-lipoic acid on skeletal muscle contractile properties. Journal of Applied Physiology. 90:1424-1430, 2001.
• Demirel H.A., S.K. Powers, M.A. Zergeroglu, R.A. Shanely, K.L. Hamilton, J. Coombes, H. Naito. Short-term exercise improves myocardial tolerance to in vivo ischemia-reperfusion in the rat. Journal of Applied Physiology. 91:2205-2212, 2001.
• Coombes, J.S., S.K. Powers, K.L. Hamilton, H.A. Demirel, R.A. Shanely, M.A. Zergeroglu, C.K. Sen, L. Packer, and L.L. Ji. Improved cardiac performance after ischemia in aged rats supplemented with vitamin E and alpha-lipoic acid. American Journal of Physiology Regulatory and Integrated Comparative Physiology. 279:R2149-R2155, 2000.
• Coombes, J.S., S.K. Powers, H.A. Demirel, K.L. Hamilton, J. Jessup, H.K. Vincent, and R.A. Shanely. Vitamin E deficiency fails to affect myocardial performance during in vivo ischemia-reperfusion. International Journal of Vitamin and Nutrition Research. 70:293-300, 2000.
• Hamilton, K.L., M.C. Meyers, W.A. Skelly, R.J. Marley. Oral creatine supplementation and upper extremity anaerobic response in females International Journal of Sport Nutrition and Exercise Metabolism. 10:277-289, 2000.
• Coombes, J.S., S.K. Powers, H.A. Demirel, J. Jessup, H.K. Vincent, K.L. Hamilton, H. Naito, R.A. Shanely, C.K. Sen, L. Packer, and L.L. Ji. Effect of combined supplementation with vitamin E and alpha-lipoic acid on myocardial performance during in vivo ischaemia-reperfusion. Acta Physiologica Scandinavica. 169:261-269, 2000.
• Coombes, J.S., and K.L. Hamilton. The effectiveness of commercially available sports drinks. Sports Medicine, 29:181-209, 2000.
• Powers, S.K., and K. Hamilton. Antioxidants and exercise. Clinics in Sports Medicine. 18:525-536, 1999.
• Powers, S.K., H.A. Demirel, H.K. Vincent, J.S. Coombes, H. Naito, K.L. Hamilton, R.A. Shanely, and J. Jessup. Exercise training improves myocardial tolerance to in vivo ischemia-reperfusion in the rat. American Journal of Physiology. 275:R1468-1477, 1998.